The economic analysis, which is published in BMJ Mental Health, compared TMS to usual care in specialist mental health services, and found that TMS reduces depressive symptoms, eases pressures on informal carers and on NHS resources, and helps people get back to work.
Despite the significant investments made in digital lab technology, ELNs often fail to support effective scientific work. Only 62 % of scientists say their ELN allows them to work efficiently, and just 5 % report being able to analyze experimental results without specialist support.
Schizophrenia affects people across all regions and backgrounds, yet most genetic studies to date have focused on individuals of European ancestry. This imbalance has limited scientific understanding of the disorder and reduced the accuracy of genetic tools for millions of people, particularly those of African ancestry.
Blood-based aging clocks suggest that shingles vaccination may modestly slow molecular aging processes in later life, without clear effects on neurodegeneration or cardiovascular health.
Sapio Sciences, the science-aware™ AI lab informatics platform, today announced the availability of trusted, third-party scientific applications and platforms now integrated directly into Sapio ELaiN, its third-generation AI lab notebook. These integrations bring well-established scientific solutions, widely used across biopharma research and development, directly into the ELaiN environment.
Sapio Sciences, the science-aware™ AI lab informatics platform, today announced that the Wellcome Sanger Institute has selected the Sapio Informatics Platform as its central LIMS to underpin the Institute’s ambitious lab transformation program. The Sanger Institute will move from a patchwork of legacy LIMS solutions to a foundation centered on Sapio LIMS to support large-scale genomic research, demand planning and lab operations.
A new UCLA study reveals that a widely used federal hospital safety metric is fundamentally flawed when applied to emergency stroke care, potentially creating incentives that may discourage hospitals from performing lifesaving procedures for the sickest patients.
Since its introduction as a clinical technique in the 1940s, ultrasound has established a firm place in the arsenal of diagnostic imaging techniques used by clinicians and researchers, due to its ability to non-invasively probe the inner structures of the body.
A recent study published in Engineering has shed new light on the role of the protein NSUN2 in the development of cardiac hypertrophy and heart failure. The research, conducted by a team from Harbin Medical University, reveals that NSUN2, a member of the NOL1/NOP2/Sun domain family, significantly contributes to pathological cardiac hypertrophy by activating the LARP1-GATA4 axis, potentially offering a novel therapeutic target for heart failure.
A recent study published in Engineering has unveiled a novel approach to generating functional organoids from human adult adipose tissue. This method, which bypasses traditional stem cell isolation and genetic manipulation, offers a more straightforward and scalable pathway for creating organoids that can be used in regenerative medicine and disease modeling.
The study, led by Kalyani Chaubey, PhD, from the Pieper Laboratory, published today in Cell Reports Medicine. Through studying diverse preclinical mouse models and human AD brains, the team showed that the brain's failure to maintain normal levels of a central cellular energy molecule, NAD+, is a major driver of AD, and that maintaining proper NAD+ balance can prevent and even reverse the disease.
Mouth cancer is the second most common malignancy in India, with an estimated 143,759 new cases and 79,979 deaths every year. Rates of the disease have risen steadily, and now stand at just under 15 for every 100,000 Indian men, note the researchers.